Wednesday, February 22, 2006
AP Info
I posted some extra help files related to our Acid/Base unit as well as some O.C. files. We return on day 2 (I think) so we will have our first Acid/Base exam two days later (day 4, as usual). I will correct your winter assignment (if there are any corrections- there should not be any because this is an open book assignment and the rules of organic chemistry are completely unambiguous and explicit) that week so that you can get some feedback before you are tested on that material.
Speaking of Organic Chemistry related to our in-class discussion of pharmacology, I pose this question : Heroin crosses the "brain-blood barrier" 100 times faster than morphine because heroin is a lipid (fat)-soluble molecule whereas morphine is not as soluble in lipids. Look at the molecules and try to account for the difference in this physical property (solubility) of these physiologically similar (and horrifyingly dangerous- did you see "House" this week?) compounds. If you know the reason, mention it in class (for a gold star and nomination for class factotem!).
Speaking of Organic Chemistry related to our in-class discussion of pharmacology, I pose this question : Heroin crosses the "brain-blood barrier" 100 times faster than morphine because heroin is a lipid (fat)-soluble molecule whereas morphine is not as soluble in lipids. Look at the molecules and try to account for the difference in this physical property (solubility) of these physiologically similar (and horrifyingly dangerous- did you see "House" this week?) compounds. If you know the reason, mention it in class (for a gold star and nomination for class factotem!).
# posted by C @ 6:24 PM 
